広がり続けるゲノム統計遺伝学の最前線を網羅する決定版ハンドブック。This two-volume edition of a classic text provides a thorough introduction to statistical genomics. It features new chapters focusing on statistical aspects of data generated by new sequencing technologies, including sequence-based functional assays. It also examines population genetics and evolutionary models and inference, with new chapters on the multi-species coalescent, admixture and ancient DNA, as well as genetic association studies including causal analyses and variant interpretation. Prev. ed.: 2007 (the title changed from Handbook of Statistical Genetics).