New in softcover. Hardcover was published in 2023. This textbook provides a comprehensive introduction to the physics of laser-plasma interactions (LPI), based on a graduate course taught by the author. The emphasis is on high-energy-density physics (HEDP) and inertial confinement fusion (ICF), with a comprehensive description of the propagation, absorption, nonlinear effects and parametric instabilities of high energy lasers in plasmas.