The book is intended for psychiatrists, psychologists, and other mental health professionals. Written by experts, the 41 chapters are divided in six sections to discuss: The natural history of bipolar disorder; Biological underpinnings; Pharmacological treatment; Psychosocial interventions; Special populations; and New approaches to diagnosis and intervention. It will also discuss the use of antipsychotics and lithium as disease modifying agents, and clinical progression and neuroprogression concepts.