With the techniques provided in this handbook, researchers, professors, and students can develop a robust bioanalytical LC-MS/MS assay method, which can ultimately be used for the development of new drugs.

Editors Li, Zhang, and Tse of the Novartis Institutes for BioMedical Research present this thick reference for LC-MS analysis of biological materials. A large number of detailed chapters are grouped into sections on overall usefulness, legal regulation, methodological best practices, and exemplary protocols. The methodological sections are the largest, including analytical technique for sample collection, both the LC and MS ends of the instrument, drug analysis in various types of matrix, peptides, nucleic acid derivatives, and lipids. Several appendices and a glossary add supplemental data useful for lab analysis. Annotation 2013 Book News, Inc., Portland, OR (booknews.com)